4-1BB

4-1BB is a member of the tumor necrosis factor (TNF) receptor family. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. It can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, 4-1BB expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. The best characterized activity of 4-1BB is its costimulatory activity for activated T cells. Crosslinking of 4-1BB enhances T cell proliferation, IL-2 secretion, survival and cytolytic activity.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3827 Recombinant 4-1BB Protein (Met1-Gln186) [His] Mammalian cells Recombinant 4-1BB Protein (Met1-Gln186) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 30 kDa. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0680Lsx Recombinant 4-1BB / TNFRSF9 Protein (Val 29-Ile 191) [His] HEK293 Cells. Rabbit 4-1BB Protein (Val 29-Ile 191) fused with a His tag at C-terminus was expressed in HEK 293 cells, with a molecular weight of 27-33 kDa. (Uniprot ID: G1SHD7) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0681Lsx Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) HEK293 Cells. Human 4-1BB low endotoxin was expressed in HEK 293 cells, with a molecular weight of 28-35 kDa. (Uniprot ID: Q07011-1) 4-1BB Tumor Antigens Datasheet 1 mg Inquiry
VAng-0682Lsx Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Fc] HEK293 Cells. Human 4-1BB low endotoxin with a Mouse IgG2a Fc Tag was expressed in HEK 293 cells, with a molecular weight of 55-66 kDa. (Uniprot ID: Q07011-1) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0683Lsx Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Avi] [His] HEK293 Cells. Biotinylated Human 4-1BB, Avi tag, His Tag, was expressed in HEK 293 cells, with a molecular weight of 28-35 kDa. (Uniprot ID: NP_001552.2) 4-1BB Tumor Antigens Datasheet 25 µg Inquiry
VAng-0684Lsx Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Avi] [Fc] HEK293 Cells. Biotinylated Human 4-1BB, Avi tag, Fc Tag, was expressed in HEK 293 cells, with a molecular weight of 55-60 kDa. (Uniprot ID: NP_001552.2) 4-1BB Tumor Antigens Datasheet 25 µg Inquiry
VAng-0685Lsx Recombinant 4-1BB / TNFRSF9 Protein (Val 24-Leu 211) [Fc] HEK293 Cells. Mouse 4-1BB, Fc tag, was expressed in HEK 293 cells, with a molecular weight of 46.7 kDa. (Uniprot ID: NP_001070976) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0686Lsx Cynomolgus / Rhesus macaque 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [His] HEK293 Cells. Cynomolgus / Rhesus macaque 4-1BB, His tag, was expressed in HEK 293 cells, with a molecular weight of 19.2 kDa. (Uniprot ID: XP_005544945.1) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0687Lsx Recombinant 4-1BB / TNFRSF9 Protein (Gln 25-Gln 186) [Fc] HEK293 Cells. Human 4-1BB, Fc Tag, was expressed in HEK 293 cells, with a molecular weight of 43.3 kDa. (Uniprot ID: NP_001552.2) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-0688Lsx Human 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [His] HEK293 Cells. Human 4-1BB, His Tag, was expressed in HEK 293 cells, with a molecular weight of 19.2 kDa. (Uniprot ID: Q07011-1) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-2776Lsx Recombinant 4-1BB / TNFRSF9 Protein E. coli Recombinant 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 20 µg Inquiry
VAng-2777Lsx Recombinant 4-1BB / TNFRSF9 Protein (aa 1-185) [Fc] E. coli Recombinant 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 50 µg Inquiry
VAng-2778Lsx Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-256) Cell Free Expression Recombinant 4-1BB / TNFRSF9 Protein was expressed in cell free expression systems. (Uniprot ID: P20334) 4-1BB Tumor Antigens Datasheet 50 µg Inquiry
VAng-2779Lsx Recombinant 4-1BB Protein (aa 1-186) [Fc] HEK 293 Cells Recombinant 4-1BB Protein, fused to the Fc portion of human IgG1, was expressed in HEK 293 cells. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 50 µg Inquiry
VAng-2780Lsx Recombinant Human 4-1BB / TNFRSF9 Protein (aa 52-254) [His] E. coli Recombinant human 4-1BB / TNFRSF9 Protein, His tag, was expressed in E. coli. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-2781Lsx Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-187) E. coli Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: P20334) 4-1BB Tumor Antigens Datasheet 100 µg Inquiry
VAng-2782Lsx Recombinant 4-1BB / TNFRSF9 Protein (CHO cells) CHO Cells Recombinant 4-1BB / TNFRSF9 Protein was expressed in CHO cells. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 200 µg Inquiry
VAng-2783Lsx Recombinant 4-1BB / TNFRSF9 Protein (aa 40-153) [His] E. coli Recombinant 4-1BB / TNFRSF9 Protein, His tag, was expressed in E. coli. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 200 µg Inquiry
VAng-2784Lsx Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-187) [Fc] HEK 293 Cells Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in HEK 293 cells. (Uniprot ID: P20334) 4-1BB Tumor Antigens Datasheet 50 µg Inquiry
VAng-2785Lsx Recombinant 4-1BB / TNFRSF9 Protein (Sf9 Baculovirus Cells) Sf9 Insect Cells Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in Sf9 Baculovirus Cells. (Uniprot ID: Q07011) 4-1BB Tumor Antigens Datasheet 10 µg Inquiry

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