Angiopoietin-2
Angiopoietin-2 is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 modulates angiogenesis in a cooperative manner with another important angiogenic factor, vascular endothelial growth factor A. Genetic studies have revealed that ANG-2 also is critical in lymphangiogenesis during development. ANG-2 has multiple physiologic effects that regulate vascular tone, hormone secretion, tissue growth and neural activity. Several reports indicate that ANG-2 can induce neovascularization in experimental systems due to the expression of different growth factors such as angiopoietin 2, vascular endothelial factor, and its receptor, fibroblast growth factor, platelet derived growth factor, transforming growth factor beta and epidermal growth factor.CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
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VAng-3043Lsx | Recombinant Bovine Angiopoietin-2 Protein (aa 1-123) | E. coli | Recombinant Bovine Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3044Lsx | Recombinant Rabbit Angiopoietin-2 Protein (aa 230-487) [His] [T7] | E. coli | Recombinant Rabbit Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3045Lsx | Recombinant Human Angiopoietin-2 Protein (aa 24-496) [His] | E. coli | Recombinant Human Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3046Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 19-496) (E. coli) | E. coli | Recombinant Rat Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3047Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 19-496) (Yeast) | Yeast | Recombinant Rat Angiopoietin-2 Protein was expressed in Yeast. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 50 µg | Inquiry | |
VAng-3048Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 19-496) (Baculovirus) | Baculovirus | Recombinant Rat Angiopoietin-2 Protein was expressed in Baculovirus. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 50 µg | Inquiry | |
VAng-3049Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 19-496) (Mammalian-Cell) | Mammalian Cells | Recombinant Rat Angiopoietin-2 Protein was expressed in Mammalian Cells. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 50 µg | Inquiry | |
VAng-3050Lsx | Recombinant Human Angiopoietin-2 Protein (aa 269-496) [His] | E. coli | Recombinant Human Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3051Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 352-477) [His] | E. coli | Recombinant Rat Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3052Lsx | Recombinant Pig Angiopoietin-2 Protein (aa 89-206) [His] [T7] | E. coli | Recombinant Pig Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3053Lsx | Recombinant Human Angiopoietin-2 Protein (CHO cells) | CHO Cells | Recombinant Human Angiopoietin-2 Protein was expressed in CHO cells. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 100 µg | Inquiry | |
VAng-3054Lsx | Recombinant Human Angiopoietin-2 Protein (Sf-9 insect cells) | Sf9 Insect Cells | Recombinant Human Angiopoietin-2 Protein was expressed in Sf-9 insect cells. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 5 µg | Inquiry | |
VAng-3055Lsx | Recombinant Mouse Angiopoietin-2 Protein (aa 19-147) [His] | E. coli | Recombinant Mouse Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O35608) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3056Lsx | Recombinant Rat Angiopoietin-2 Protein (aa 33-243) [His] | E. coli | Recombinant Rat Angiopoietin-2 Protein was expressed in E. coli. (Uniprot ID: O35462) | Angiopoietin-2 | Tumor Antigens | 200 µg | Inquiry | |
VAng-3057Lsx | Recombinant Human Angiopoietin-2 Protein (19-496) [His] | CHO Cells | Recombinant Human Angiopoietin-2 Protein was expressed in CHO cells. (Uniprot ID: O15123) | Angiopoietin-2 | Tumor Antigens | 50 µg | Inquiry |
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