Beta-Catenin

Beta-Catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. It is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is associated with many cancers, including hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors, ovarian and endometrial cancer. Alterations in the localization and expression levels of beta-catenin have been associated with various forms of heart disease, including dilated cardiomyopathy. Altered expression profiles in beta-catenin have been associated with dilated cardiomyopathy in humans. Beta-catenin upregulation of expression has generally been observed in patients with dilated cardiomyopathy. In the presence of Wnt ligand, beta-Catenin is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. CTNNB1 is involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr4064 Recombinant Human beta-Catenin Protein (aa 1-781) [GST] Human Recombinant Human beta-Catenin Protein (Met1-Leu781) fused with a GST tag at N-terminus was expressed in Baculovirus-Insect Cells, with a molecular weight of 113kDa. (Accession ID: P35222-1) Beta-Catenin Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr4065 Recombinant Mouse beta-Catenin Protein (aa 1-781) [GST] Mouse Recombinant Mouse beta-Catenin Protein (Met1-Leu781) fused with a GST tag at N-terminus was expressed in Baculovirus-Insect Cells, with a molecular weight of 113kDa. (Accession ID: Q02248) Beta-Catenin Tumor Antigens Datasheet 20 µg Inquiry
VAng-3785Lsx Recombinant Rat Xenopus laevis CTNNB1 Protein (aa 2-781) (E. coli) E. coli Recombinant Rat beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: Q9WU82) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3786Lsx Recombinant Rat Xenopus laevis CTNNB1 Protein (aa 2-781) (Yeast) Yeast Recombinant Rat beta-Catenin (CTNNB1) Protein, expressed in Yeast. (Uniprot ID: Q9WU82) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3787Lsx Recombinant Rat Xenopus laevis CTNNB1 Protein (aa 2-781) (Baculovirus) Baculovirus Recombinant Rat beta-Catenin (CTNNB1) Protein, expressed in Baculovirus. (Uniprot ID: Q9WU82) Beta-Catenin Tumor Antigens Datasheet 50 µg Inquiry
VAng-3788Lsx Recombinant Rat Xenopus laevis CTNNB1 Protein (aa 2-781) (Mammalian-Cell) Mammalian Cells Recombinant Rat beta-Catenin (CTNNB1) Protein, expressed in Mammalian Cells. (Uniprot ID: Q9WU82) Beta-Catenin Tumor Antigens Datasheet 50 µg Inquiry
VAng-3789Lsx Recombinant Human Xenopus laevis CTNNB1 Protein E. coli Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 100 µg Inquiry
VAng-3790Lsx Recombinant Human Xenopus laevis CTNNB1 Protein (aa 2-781) (E. coli) E. coli Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3791Lsx Recombinant Human Xenopus laevis CTNNB1 Protein (aa 2-781) (Yeast) Yeast Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in Yeast. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3792Lsx Recombinant Human Xenopus laevis CTNNB1 Protein (aa 1-781) [GST] E. coli Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3793Lsx Recombinant Human Xenopus laevis CTNNB1 Protein (aa 1-781) [GST] (Sf9 insect cells) Sf9 insect cells Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in Sf9 insect cells. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 20 µg Inquiry
VAng-3794Lsx Recombinant Mouse Xenopus laevis CTNNB1 Protein Baculovirus Recombinant Mouse beta-Catenin (CTNNB1) Protein, expressed in Baculovirus. (Uniprot ID: Q02248) Beta-Catenin Tumor Antigens Datasheet 10 µg Inquiry
VAng-3795Lsx Recombinant Mouse Xenopus laevis CTNNB1 Protein (aa 508-762) [His] E. coli Recombinant Mouse beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: Q02248) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3796Lsx Recombinant Human Xenopus laevis CTNNB1 Protein (aa 439-675) [His] E. coli Recombinant Human beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: P35222) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry
VAng-3797Lsx Recombinant Rat Xenopus laevis CTNNB1 Protein (aa 409-665) [His] E. coli Recombinant Rat beta-Catenin (CTNNB1) Protein, expressed in E. coli. (Uniprot ID: Q9WU82) Beta-Catenin Tumor Antigens Datasheet 200 µg Inquiry

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