C-Met
c-Met is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its splicing isoform (NK1, NK2) are the only known ligands of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF/SF is restricted to cells of mesenchymal origin. Abnormal MET activation in cancer correlates with poor prognosis, where aberrantly active MET triggers tumor growth, formation of new blood vessels (angiogenesis) that supply the tumor with nutrients, and cancer spread to other organs (metastasis). MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr4007 | Recombinant Human c-Met Protein (aa 1-932) [Fc] | Human | Recombinant Human c-Met Protein (Met 1-Thr 932) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 129.5 kDa. (Accession ID: NP_000236) | c-Met | Tumor Antigens |  |
100 µg | Inquiry |
| VAng-Cr4008 | Recombinant Human c-Met Protein (aa 956-1390) [GST] | Human | Recombinant Human c-Met Protein (Lys956-Ser1390) fused with a GST tag at N-terminus was expressed in Baculovirus-Insect Cells, with a molecular weight of 76.8 kDa. (Accession ID: P08581-1) | c-Met | Tumor Antigens | |
50 µg | Inquiry |
| VAng-Cr4009 | Recombinant Rat c-Met Protein (aa 1-932) [Fc] | Rat | Recombinant Rat c-Met Protein (Met1-Asn932) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 128.1 kDa. (Accession ID: Q2IBC7) | c-Met | Tumor Antigens | |
50 µg | Inquiry |
| VAng-Cr4010 | Recombinant Cynomolgus c-Met Protein (aa 1-932) [Fc] | Cynomolgus | Recombinant Cynomolgus c-Met Protein (Met1-Thr932) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 128.3 kDa. (Accession ID: NP_001162100.1) | c-Met | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4011 | Recombinant Mouse c-Met Protein (aa 1-929) [Fc] | Mouse | Recombinant Mouse c-Met Protein (Met 1-Asn 929) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 128 kDa. (Accession ID: NP_032617.2) | c-Met | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4012 | Recombinant Mouse c-Met Protein (aa 1-932) [Fc] | Mouse | Recombinant Mouse c-Met Protein (Met 1-Thr 932) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 129.5 kDa. (Accession ID: NP_000236) | c-Met | Tumor Antigens | |
20 µg | Inquiry |
| VAng-1718Lsx | Human HGF R Protein (Glu 25-Thr 932) [Fc] | HEK293 Cells. | Human HGF R (c-Met), Fc tag, is expressed in human 293 cells. (Uniprot ID: AAI30421.1) | c-Met | Tumor Antigens | |
200 µg | Inquiry |
| VAng-1719Lsx | Human HGF R Protein (Glu 25-Thr 932) [His] | HEK293 Cells. | Human HGF R (c-Met), His tag, is expressed in human 293 cells. (Uniprot ID: AAI30421.1) | c-Met | Tumor Antigens | |
200 µg | Inquiry |
| VAng-1720Lsx | Human HGF R Protein (Glu 25-Thr 932) [His] [Avi] | HEK293 Cells. | Biotinylated Human HGF R (c-Met), His tag and Avi tag, is expressed in human 293 cells. (Uniprot ID: AAI30421.1) | c-Met | Tumor Antigens | |
25 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
