CA-50

CA-50, a novel cancer-associated carbohydrate marker, is detected by the C 50 antibody that has been obtained by immunization of mice with a human colorectal adenocarcinoma cell line. This antibody that defines CA 50 reacts with both the afucosyl form of sialylated Lewis(a) carbohydrate moiety and sialylated Lewis(a) moiety which is also the antigenic epitope in the CA 19-9 assay. CA 50 is not organ-specific and its elevated levels in serum can be observed in a variety of malignancies, especially gastrointestinal cancers. In contrast to CA 19-9, high CA 50 levels can also be seen in malignant tumors outside the digestive tract. The expectation, that CA 50 might be positive in the Lewis negative patients who cannot synthesize CA 19-9, is supported by the histoimmunologic study.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3877 Cancer Antigen 50 Antigen Human Cell Culture Cancer Antigen 50 Antigen, Host/Source: Human Cell Culture. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2. CA-50 Tumor Antigens Datasheet 50 kU Inquiry
VAng-Wyb8636 Recombinant CA-50 Protein Cell Culture. CA-50, Calibrator Grade, recombinant protein from Cell Culture, 40681 U/mL. CA-50 Tumor Antigens Datasheet 50 ku Inquiry

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