CD20

CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The protein has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3914 Recombinant Human CD20 Protein (aa 141-188) [TrxA] Human Recombinant Human CD20 Protein (Ile141-Ser188) fused with a TrxA tag at N-terminus was expressed in E. coli, with a molecular weight of 23.9 kDa. (Accession ID: NP_068769.2) CD20 Tumor Antigens Datasheet 20 µg Inquiry
VAng-Cr3915 Recombinant Ferret CD20 Protein (aa 213-297) [His] Ferret Recombinant Ferret CD20 Protein (Glu213-Pro297) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 11.3 kDa. CD20 Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr3916 Recombinant Cynomolgus CD20 Protein (aa 213-297) [His] Cynomolgus Recombinant Cynomolgus CD20 Protein (Glu213-Pro297) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 12.1 kDa. (Accession ID: NP_001274241.1) CD20 Tumor Antigens Datasheet 100 µg Inquiry
VAng-1214Lsx Recombinant CD20 Protein (Full Length) [His] HEK293 Cells. Human CD20, His tag, is expressed in HEK 293 cells. (Uniprot ID: P11836-1) CD20 Tumor Antigens Datasheet 20 µg Inquiry
VAng-1215Lsx Recombinant CD20 Protein (Met 1-Pro 297) [His] HEK293 Cells. Human CD20, His tag, is expressed in HEK 293 cells. (Uniprot ID: P11836-1) CD20 Tumor Antigens Datasheet 20 µg Inquiry

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