CRBN

CRBN is a protein that in humans is encoded by CRBN gene. The gene that encodes the cereblon protein is found on the human chromosome 3, on the short arm at position p26.3 from base pair 3,190,676 to base pair 3,221,394. CRBN orthologs are highly conserved from plants to human. Mutations in this gene are associated with autosomal recessive nonsyndromic intellectual disability, possibly as a result of dysregulation of calcium-activated potassium channels in the brain during development. It can also bind to the large-conductance calcium-activated potassium channel (KCNMA1) and regulates its activity.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3790 Recombinant CRBN Protein (Met1-Leu442) [His] Mammalian cells Recombinant CRBN Protein (Met1-Leu442) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 48.62 kDa. (Uniprot ID: Q96SW2) CRBN Tumor Antigens Datasheet 100 µg Inquiry

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