DR6

TNFRSF21 (TNF Receptor Superfamily Member 21) is a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1473Lsx Recombinant DR6 Protein (Gln 42-Leu 350) [Fc] HEK293 Cells. Human DR6 (TNFRSF25), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH17730) DR6 Tumor Antigens Datasheet 200 µg Inquiry

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