E-Cadherin
E-Cadherin is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells, and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.E-cadherin (epithelial) is the most well-studied member of the cadherin family. It consists of 5 cadherin repeats (EC1 - EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3956 | Recombinant Human E-Cadherin Protein (aa 1-707) [Fc] | Human | Recombinant Human E-Cadherin Protein (Met1-Ile707) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 87.1 kDa. (Accession ID: P12830) | E-Cadherin | Tumor Antigens |  |
50 µg | Inquiry |
| VAng-Cr3957 | Recombinant Human E-Cadherin Protein (aa 1-707) [His] | Human | Recombinant Human E-Cadherin Protein (Met1-Ile707) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 77 kDa. (Accession ID: NP_004351.1) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr3958 | Recombinant Human E-Cadherin Protein (aa 155-709) [His] | Human | Recombinant Human E-Cadherin Protein (Asp155-Ala709) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 62 kDa. (Accession ID: NP_004351.1) | E-Cadherin | Tumor Antigens | |
50 µg | Inquiry |
| VAng-Cr3959 | Recombinant Rat E-Cadherin Protein (aa 1-713) [Fc] | Rat | Recombinant Rat E-Cadherin Protein (Met1-Ala713) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 103.8 kDa. (Accession ID: Q9R0T4) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr3960 | Recombinant Human E-Cadherin Protein (aa 1-709) [His] | Human | Recombinant Human E-Cadherin Protein (Met1-Ala709) fused with a His tag at C-terminus was expressed in Baculovirus-Insect Cells, with a molecular weight of 77.2 kDa. (Accession ID: NP_004351.1) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr3961 | Recombinant Mouse E-Cadherin Protein (aa 1-709) [His] | Mouse | Recombinant Mouse E-Cadherin Protein (Met 1-Val 709) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 78 kDa. (Accession ID: P09803) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr3962 | Recombinant Rat E-Cadherin Protein (aa 1-713) [His] | Rat | Recombinant Rat E-Cadherin Protein (Met1-Ala713) fused with a His tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 78.4 kDa. (Accession ID: Q9R0T4) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
| VAng-1474Lsx | Recombinant E-Cadherin Protein (Gln 23-Pro 621) [Fc] | HEK293 Cells. | Human E-Cadherin, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI41839) | E-Cadherin | Tumor Antigens | |
100 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
