EDDP

EDDP is a major metabolite of methadone that can be found in urine. Methadone is an opioid used for opioid maintenance therapy, to help with tapering in people with opioid dependence, and for pain. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use. Side effects are similar to those of other opioids. Commonly these include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and a decreased effort to breathe.EDDP is cyclic in structure which makes it very difficult to detect using an immunoassay targeted to the native compound methadone.so EDDP represents a better urine marker for methadone maintenance.

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