ICOSL
ICOSL is a protein that in humans is encoded by ICOSL gene. ICOSLG promotes an 'entangled' mode of follicular T-helper/B-cell interactions, characterized by brief but extensive surface engagement, productive T-cell calcium spikes, and B-cell acquisition of CD40 signals. Reiterated entanglement promotes outer zone colocalization of outcompeting germinal center B cells together with follicular T-helper cells, affording the former increased access to T-cell help. ICOSLG on germinal center B cells is upregulated by CD40 signals.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3845 | Recombinant ICOSL Protein (Met1-Ser258) [His] | Mammalian cells | Recombinant ICOSL Protein (Met1-Ser258) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 45 kDa. (Uniprot ID: O75144) | ICOSL | Tumor Antigens |  |
100 µg | Inquiry |
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