IGF1R

IGF1R (Insulin Like Growth Factor 1 Receptor) binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1658Lsx Cynomolgus IGF-I R Protein (Glu 31-Asn 932) HEK293 Cells. Cynomolgus IGF-I R (CD221) is expressed in human 293 cells. (Uniprot ID: G7P9I7-1) IGF1R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1749Lsx Human IGF-I R Protein (Glu 31-Asn 932) HEK293 Cells. Human IGF-I R (CD221) is expressed in human 293 cells. (Uniprot ID: P08069-1) IGF1R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1928Lsx Mouse IGF-I R Protein (Glu 31-His 936) HEK293 Cells. Mouse IGF-I R (CD221) is expressed in human 293 cells. (Uniprot ID: Q60751-1) IGF1R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1952Lsx Rat IGF-I R Protein (Glu 31-His 936) HEK293 Cells. Rat IGF-I R (CD221) is expressed in human 293 cells. (Uniprot ID: P24062-1) IGF1R Tumor Antigens Datasheet 100 µg Inquiry

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