IKZF1
IKZF1 is a protein that in humans is encoded by IKZF1 gene. It has been found in recent years to be a major tumor suppressor involved in human B-cell acute lymphoblastic leukemia. IKZF1 is upregulated in granulocytes, B cells, CD4 and CD8 T cells, and NK cells, and downregulated in erythroblasts, megakaryocytes and monocytes. SNPs located near the 3' region of IKZF1 in humans have been linked to susceptibility to childhood acute lymphoblastic leukemia (ALL) as well as type I diabetes. It also displays crucial functions in the hematopoietic system and its loss of function has been linked to the development of lymphoid leukemia.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3791 | Recombinant IKZF1 Protein (Met1-Ser519) [MYC/DDK] | Mammalian cells | Recombinant IKZF1 Protein (Met1-Ser519) fused with a MYC/DDK tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 57.09 kDa. (Uniprot ID: Q13422) | IKZF1 | Tumor Antigens |  |
100 µg | Inquiry |
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