IL10

IL10 (Interleukin 10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1758Lsx Human IL-10 Protein (Ser 19-Ser 178) [His] HEK293 Cells. Human IL-10, His tag, is expressed in human 293 cells. (Uniprot ID: NP_000563.1) IL10 Tumor Antigens Datasheet 20 µg Inquiry
VAng-1929Lsx Mouse IL-10 Protein (Ser 19-Ser 178) [His] HEK293 Cells. Mouse IL-10, His tag, is expressed in human 293 cells. (Uniprot ID: NP_034678) IL10 Tumor Antigens Datasheet 20 µg Inquiry

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