IL13

IL13 is a protein that in humans is encoded by IL13 gene. It has a mass of 13 kDa and folds into 4 alpha helical bundles. The secondary structural features of IL-13 are similar to that of Interleukin 4 (IL-4), however it only has 25% sequence homology to IL-4 and is capable of IL-4 independent signaling. IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, Natural killer T cell, Mast cell, Basophil cells, Eosinophil cells and Nuocyte cells. Interleukin-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis and chitinase up-regulation. It is a mediator of allergic inflammation and different diseases including asthma.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3806 Recombinant IL13 Protein (Gly35-Asn146) [Fc] Mammalian cells Recombinant IL13 Protein (Gly35-Asn146) fused with a Fc tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 50-55 kDa. (Uniprot ID: P35225) IL13 Tumor Antigens Datasheet 100 µg Inquiry
VAng-1769Lsx Human IL-13 Protein (Gly 21-Asn 132) HEK293 Cells. Human IL-13 is expressed in human 293 cells. (Uniprot ID: AAK53823.1) IL13 Tumor Antigens Datasheet 50 µg Inquiry
VAng-1770Lsx Human IL-13 Protein (Gly 21-Asn 132) [Fc] HEK293 Cells. Human IL-13, Fc tag, is expressed in human 293 cells. (Uniprot ID: AAK53823.1) IL13 Tumor Antigens Datasheet 50 µg Inquiry
VAng-1771Lsx Human IL-13 Protein (Gly 21-Asn 132) [His] HEK293 Cells. Human IL-13, His tag, is expressed in human 293 cells. (Uniprot ID: AAK53823.1) IL13 Tumor Antigens Datasheet 50 µg Inquiry
VAng-1772Lsx Human IL-13 Protein (Leu 25-Asn 146) [Fc] HEK293 Cells. Human IL-13, Fc tag, is expressed in human 293 cells. (Uniprot ID: NP_002179.2) IL13 Tumor Antigens Datasheet 50 µg Inquiry

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