IL6
IL6 is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. It is capable of crossing the blood-brain barrier and initiating synthesis of PGE2 in the hypothalamus, thereby changing the body's temperature setpoint. It can be secreted by macrophages in response to specific microbial molecules, referred to as pathogen-associated molecular patterns (PAMPs). These PAMPs bind to an important group of detection molecules of the innate immune system, called pattern recognition receptors (PRRs), including Toll-like receptors (TLRs). These are present on the cell surface and intracellular compartments and induce intracellular signaling cascades that give rise to inflammatory cytokine production.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3776 | Recombinant IL6 Protein (Met1-Met212) [Fc] | Mammalian cells | Recombinant IL6 Protein (Met1-Met212) fused with a Fc tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 55 kDa. (Uniprot ID: P05231) | IL6 | Tumor Antigens |  |
100 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
