INSR
INSR is a protein that in humans is encoded by INSR gene. It is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of tyrosine kinase receptors. Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis, a functional process that under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer. Transcription of alternative splice variants derived from the INSR gene are translated to form one of two monomeric isomers; IR-A in which exon 11 is excluded, and IR-B in which exon 11 is included. Inclusion of exon 11 results in the addition of 12 amino acids upstream of the intrinsic furin proteolytic cleavage site.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3793 | Recombinant INSR Protein (Met1-Ser758) [His] | Mammalian cells | Recombinant INSR Protein (Met1-Ser758) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 83.38 kDa. (Uniprot ID: P06213) | INSR | Tumor Antigens |  |
100 µg | Inquiry |
| VAng-1838Lsx | Human Insulin R Protein (His 28-Lys 944) [His] | HEK293 Cells. | Human Insulin R (INSR) protein, His tag, expressed in human 293 cells. (Uniprot ID: P06213-2) | INSR | Tumor Antigens | |
100 µg | Inquiry |
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