LRP5

LRP5 (LDL Receptor Related Protein 5) is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1900Lsx Human LRP5 Protein (Glu 644-Gln 1263) [Fc] HEK293 Cells. Human LRP5 protein, Mouse IgG2a Fc Tag, expressed in human 293 cells. (Uniprot ID: O75197-1) LRP5 Tumor Antigens Datasheet 100 µg Inquiry

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