Nectin-1

NECTIN1 (Nectin Cell Adhesion Molecule 1) is an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2581Lsx Human Nectin-1 Protein (Gln 31-Thr 334) [Fc] HEK293 cells Human Nectin-1 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: Q15223-1) Nectin-1 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2582Lsx Human Nectin-1 Protein (Gln 31-Thr 334) [His] HEK293 cells Human Nectin-1 protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_002846) Nectin-1 Tumor Antigens Datasheet 100 µg Inquiry

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