NKG2D

KLRK1 (Killer Cell Lectin Like Receptor K1) is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2607Lsx Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified) HEK293 cells Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1) NKG2D Tumor Antigens Datasheet 100 µg Inquiry
VAng-2608Lsx Human NKG2D Protein (Ile 73-Val 216) [Fc] HEK293 cells Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) NKG2D Tumor Antigens Datasheet 100 µg Inquiry
VAng-2609Lsx Human NKG2D Protein (Ile 73-Val 216) [His] HEK293 cells Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) NKG2D Tumor Antigens Datasheet 100 µg Inquiry

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