Oncostatin M

OSM (Oncostatin M) is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Diseases associated with OSM include Kaposi Sarcoma and Indolent Myeloma.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2622Lsx Human OSM Protein (Ala 26-Arg 252) HEK293 cells Human Oncostatin M protein, was expressed in human 293 cells. (Uniprot ID: NP_065391.1) Oncostatin M Tumor Antigens Datasheet 50 µg Inquiry

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