Orf Virus

Orf Virus (ORFV or OV) belongs to the Poxviridae family, genus Parapoxvirus. Orf is a zoonotic disease, meaning humans can contract this disorder through direct contact with infected sheep and goats or with fomites carrying the orf virus. The infection of orf virus usually occurs when the broken skins get in touch with virus from the infected animals or the surface of equipments contaminated with orf virus, the injection is often confined to epidermis of the skin and commonly without systemic symptoms. Infection of orf virus causes a purulent-appearing papule locally in humans, which can be located in fingers, hands, arms, and faces. While orf is usually a benign self-limiting illness, it can be very progressive and even life-threatening in the immune-compromised host.

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