OX40

OX40 is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. It has no effect on the proliferative abilities of CD4+ cells for the first three days, however after this time proliferation begins to slow and cells die at a greater rate, due to an inability to maintain a high level of PKB activity and expression of Bcl-2, Bcl-XL and survivin.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3829 Recombinant OX40 Protein (Met1-Ala216) [His] Mammalian cells Recombinant OX40 Protein (Met1-Ala216) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 40-45 kDa. (Uniprot ID: P43489) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2627Lsx Biotinylated Mouse OX40 Protein (Val 20-Pro 211) [His] [Avi] HEK293 cells Biotinylated Mouse OX40 protein, His tag and Avi tag, was expressed in human 293 cells. (Uniprot ID: P47741-1) OX40 Tumor Antigens Datasheet 25 µg Inquiry
VAng-2628Lsx Human OX40 Protein (Leu 29-Ala 216) [Mouse IgG2a Fc Tag] HEK293 cells Human OX40 protein, Mouse IgG2a Fc Tag, was expressed in human 293 cells. (Uniprot ID: P43489-1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2629Lsx Marmoset OX40 Protein (Leu 29-Ala 214) [His] HEK293 cells Marmoset OX40 protein, His tag, was expressed in human 293 cells. (Uniprot ID: F7DHA3-1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2630Lsx Biotinylated Human OX40 Protein (Leu 29-Ala 216) [His] [Avi] HEK293 cells Biotinylated Human OX40 protein, His tag and Avi tag, was expressed in human 293 cells. (Uniprot ID: NP_003318.1) OX40 Tumor Antigens Datasheet 25 µg Inquiry
VAng-2631Lsx Rat OX40 Protein (Val 20-Pro 210) [Fc] HEK293 cells Rat OX40 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P15725) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2632Lsx Rabbit OX40 Protein (Ala 19-Gln 208) [Fc] HEK293 cells Rabbit OX40 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: O02764) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2633Lsx Biotinylated Human OX40 Protein (Leu 29-Ala 216) [Fc] [Avi] HEK293 cells Biotinylated Human OX40 protein, human IgG1 Fc tag and Avi tag, was expressed in human 293 cells. (Uniprot ID: NP_003318) OX40 Tumor Antigens Datasheet 25 µg Inquiry
VAng-2634Lsx Rhesus macaque OX40 Protein (Lys 28-Ala 214) [Fc] HEK293 cells Rhesus macaque OX40 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: XP_001090870.1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2635Lsx Rhesus macaque OX40 Protein (Lys 28-Ala 214) [His] HEK293 cells Rhesus macaque OX40 protein, His tag, was expressed in human 293 cells. (Uniprot ID: XP_001090870.1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2636Lsx Mouse OX40 Protein (Val 20-Pro 211) [Fc] HEK293 cells Mouse OX40 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: NP_035789) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2637Lsx Mouse OX40 Protein (Val 20-Pro 211) [His] HEK293 cells Mouse OX40 protein, His tag, was expressed in human 293 cells. (Uniprot ID: P47741-1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2638Lsx Human OX40 Protein (Leu 29-Ala 216) [His] HEK293 cells Human OX40 protein, His tag, was expressed in human 293 cells. (Uniprot ID: P43489-1) OX40 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2639Lsx Human OX40 Protein (Leu 29-Ala 216) [human IgG1 Fc tag] HEK293 cells Human OX40 protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: NP_003318) OX40 Tumor Antigens Datasheet 100 µg Inquiry

All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.

Shopping Basket