PD-L1
PD-L1 is a protein that in humans is encoded by PD-L1 gene. It is a 40kDa type I transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the immune system reacts to foreign antigens that are associated with exogenous or endogenous danger signals, which triggers a proliferation of antigen-specific CD8+ T cells and/or CD4+ helper cells. The binding of PD-L1 to PD-1 or B7.1 transmits an inhibitory signal that reduces the proliferation of antigen-specific T-cells in lymph nodes, while simultaneously reducing apoptosis in regulatory T cells (anti-inflammatory, suppressive T cells) - further mediated by a lower regulation of the gene Bcl-2.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3817 | Recombinant PD-L1 Protein (Met1-Arg238) [His] | Mammalian cells | Recombinant PD-L1 Protein (Met1-Arg238) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 35 kDa. (Uniprot ID: Q9NZQ7) | PD-L1 | Tumor Antigens |  |
100 µg | Inquiry |
| VAng-Cr4033 | Recombinant Human PD-L1 Protein (aa 1-239) [Fc] | Human | Recombinant Human PD-L1 Protein (Met1-Thr 239) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 52 kDa. (Accession ID: NP_054862.1) | PD-L1 | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4034 | Recombinant Cynomolgus PD-L1 Protein (aa 1-239) [Fc] | Cynomolgus | Recombinant Cynomolgus PD-L1 Protein (Met1-Thr 239) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 52.3 kDa. (Accession ID: XP_015292694.1) | PD-L1 | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4035 | Recombinant Mouse PD-L1 Protein (aa 1-239) [Fc] | Mouse | Recombinant Mouse PD-L1 Protein (Met1-His239) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 51.6 kDa. (Accession ID: NP_068693.1) | PD-L1 | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4036 | Recombinant Rat PD-L1 Protein (aa 1-238) [Fc] | Rat | Recombinant Rat PD-L1 Protein (Met1-Thr238) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 51.8 kDa. (Accession ID: NP_001178883.1) | PD-L1 | Tumor Antigens | |
100 µg | Inquiry |
| VAng-Cr4037 | Recombinant Canine PD-L1 Protein (aa 1-236) [Fc] | Canine | Recombinant Canine PD-L1 Protein (Met1-Arg236) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 51.5 kDa. (Accession ID: XP_541302.4) | PD-L1 | Tumor Antigens | |
100 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
