PDCD1

PDCD1 is a protein on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity. This prevents autoimmune diseases, but it can also prevent the immune system from killing cancer cells. It is an immune checkpoint and guards against autoimmunity through two mechanisms. First, it promotes apoptosis (programmed cell death) of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells (anti-inflammatory, suppressive T cells).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3778 Recombinant PDCD1 Protein (Met1-Val170) [His] Mammalian cells Recombinant PDCD1 Protein (Met1-Val170) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 40 kDa. (Uniprot ID: Q15116) PDCD1 Tumor Antigens Datasheet 100 µg Inquiry

All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.

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