PDCD1LG2

PDCD1LG2 is a protein that in humans is encoded by PDCD1LG2 gene. PDCD1LG2 expression is inversely associated with Crohn's-like lymphoid reaction to colorectal cancer. It plays a possible role of PDCD1LG2-expressing tumor cells in inhibiting the development of tertiary lymphoid tissues during colorectal carcinogenesis. It is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3808 Recombinant PDCD1LG2 Protein (Met1-Pro219) [His] Mammalian cells Recombinant PDCD1LG2 Protein (Met1-Pro219) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 40-45 kDa. (Uniprot ID: Q9BQ51) PDCD1LG2 Tumor Antigens Datasheet 100 µg Inquiry

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