SEMA4A

SEMA4A (Semaphorin 4A) is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2688Lsx Human Semaphorin 4A Protein (Gly 33-His 683) [His] HEK293 cells Human Semaphorin 4A (SEMA4A) protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH20974) SEMA4A Tumor Antigens Datasheet 100 µg Inquiry

All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.

Shopping Basket