SMAC

DIABLO (Diablo IAP-Binding Mitochondrial Protein) is an inhibitor of apoptosis protein (IAP)-binding protein. The mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2750Lsx Human SMAC Protein (Ala 56-Asp 239) [His] HEK293 cells Human SMAC protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_063940) SMAC Tumor Antigens Datasheet 200 µg Inquiry

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