TFPI

TFPI (Tissue Factor Pathway Inhibitor) a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. Diseases associated with TFPI include Hemophilia and Thrombosis.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2766Lsx Rhesus macaque TFPI Protein (Asp 29-Lys 282) [His] HEK293 cells Rhesus macaque TFPI protein, His tag, was expressed in human 293 cells. (Uniprot ID: Q28864) TFPI Tumor Antigens Datasheet 50 µg Inquiry
VAng-2767Lsx Biotinylated Human TFPI Protein (Asp 29-Lys 282) [His] HEK293 cells Biotinylated Human TFPI protein, His tag, primary amine labeling, was expressed in human 293 cells. (Uniprot ID: NP_006278.1) TFPI Tumor Antigens Datasheet 25 µg Inquiry
VAng-2768Lsx Human TFPI Protein (Asp 29-Lys 282) [His] HEK293 cells Human TFPI protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_006278.1) TFPI Tumor Antigens Datasheet 50 µg Inquiry

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