TNFRSF11A

TNFRSF11A (TNF Receptor Superfamily Member 11a) is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2649Lsx Human RANK Protein (Ile 30-Pro 212) [Fc] HEK293 cells Human RANK (TNFRSF11A) protein, Mouse IgG2a Fc Tag, was expressed in human 293 cells. (Uniprot ID: Q9Y6Q6-1) TNFRSF11A Tumor Antigens Datasheet 100 µg Inquiry

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