TNFRSF8
TNFRSF8 is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappa B. It is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. It is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3774 | Recombinant TNFRSF8 Protein (Met1-Lys379) [His] | Mammalian cells | Recombinant TNFRSF8 Protein (Met1-Lys379) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 75-90 kDa. (Uniprot ID: P28908) | TNFRSF8 | Tumor Antigens |  |
100 µg | Inquiry |
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