TNFRSF9
TNFRSF9 is a member of the tumor necrosis factor (TNF) receptor family. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. It can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion, survival and cytolytic activity.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3814 | Recombinant TNFRSF9 Protein (Met1-Gln186) [His] | Mammalian cells | Recombinant TNFRSF9 Protein (Met1-Gln186) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 30 kDa. (Uniprot ID: Q07011) | TNFRSF9 | Tumor Antigens |  |
100 µg | Inquiry |
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