VISTA
VISTA is a protein which in humans is encoded by VISTA gene. Diseases associated with VISTA include Parasagittal Meningioma and Solar Retinopathy. Among its related pathways are NF-kappa B Signaling and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. It is approximately 50 kDa and belongs to the immunoglobulin superfamily and has one IgV domain. It is produced at high levels in tumor-infiltrating lymphocytes, such as myeloid-derived suppressor cells and regulatory T cells, and its blockade with an antibody results in delayed tumor growth in mouse models of melanoma and squamous cell carcinoma.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3824 | Recombinant VISTA Protein (Met1-Ala194) [His] | Mammalian cells | Recombinant VISTA Protein (Met1-Ala194) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 21.34 kDa. (Uniprot ID: Q9H7M9) | VISTA | Tumor Antigens |  |
100 µg | Inquiry |
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