Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsVasoactive intestinal polypeptide receptors are class B G protein-coupled receptors (GPCRs) and are receptors for the vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP). VIPs and PACAPs are members of a superfamily of structurally related peptide hormones that mediate diverse and important physiological and biological functions. VIPs and PACAPs act via three different receptors: VIPR1, VIPR2, and PAC1. PAC1 receptors are selective for PACAP, whereas VIPR1 and VIPR2 respond to both VIP and PACAP with high affinity. These receptors have been identified in various tissues, including brain, lung, kidney, gastrointestinal tract, tongue, and also on immunocompetent cells. In the CNS, these receptors function in the control of circadian rhythms, learning and memory, anxiety and responses to stress and brain injury. In the periphery, they are involved in the control of immunity and inflammation, the control of pancreatic insulin secretion, the release of catecholamines from the adrenal medulla, and as co-transmitters in autonomic and sensory neurons.
Here, we give a separate introduction and a brief summary of part of the vasoactive intestinal polypeptide receptors focusing on our current understanding of their structure, pharmacology and functions, and their likely physiological roles in health and disease.
To help strengthen our knowledge about these receptors and promote future therapeutic applications, Creative Biolabs is now offering services in every step of the membrane protein preparation process, including expression, solubilization, stabilization, and purification. We now introduce our comprehensive and versatile Magic™ membrane protein production platform to help handle these difficult-to-prepare targets and facilitate the in vitro studies. We can reconstitute your proteins into various membrane mimetics, including detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, etc.
Moreover, supported by our Magic™ membrane protein antibody discovery platform, we can further provide antibody discovery services targeting these membrane proteins. We also present DNA immunization service for anti-membrane protein antibody development. Contact us for more detailed information about our membrane protein preparation services.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
