Yeast surface display is a reliable, versatile, and quantitative technique for generating antibodies with tailored properties. It is now widely employed for screening libraries of antibody fragments with high success. Creative Biolabs has a distinguished track record in antibody discovery services, accelerating biopharmaceutical development, and overcoming significant challenges. Our proprietary yeast display antibody library construction service has consistently helped clients discover the antibodies they need.
At Creative Biolabs, we are committed to facilitating the discovery of high-affinity antibodies for your research and therapeutic needs. Our advanced techniques and expert team ensure the creation of robust, high-quality libraries tailored to your specific targets. Leveraging our efficient and validated Ultraff™ Yeast Display Platform, we provide precise library quality control to sample genetic diversity and verify the integrity and functionality of displayed antibodies.
An efficient and validated system of yeast display antibody library construction for novel binding proteins and high-affinity fragments to a specified target.
Custom antibody libraries based on your specific requirements, using various sources such as immune libraries from immunized animals, naïve libraries from non-immunized sources, and semi-synthetic or synthetic libraries from designed synthetic DNA sources.
Library quality control to sample genetic diversity and verify that most clones are of full length (optional but recommended) to boast high diversity, increasing the likelihood of identifying antibodies with the desired properties.
We offer customized solutions for various formats of antibody libraries tailored to your specific requirements, including but not limited to:
Related Services
We are also proud to provide other yeast display library construction services, including but not limited to:
Yeast Display Non-Antibody Protein Library Construction
Yeast Display Peptide Library Construction
Yeast Display cDNA Library Construction
For years, yeast display has been recognized as a robust, versatile, and quantitative method for isolating and engineering antibody fragments. Key advantages include the ease of constructing diverse libraries and the ability to perform quantitative, real-time assessment of candidate clones through flow cytometric analysis.
We have designed the library plasmid and constructed an scFv antibody library with a capacity of 107. This library features a 100% insert ratio, with a positive accuracy rate validated at 75% through DNA sequencing. The scFv antibody display efficiency, detected by FACS, exceeds 80%.
Library size | 108 | Insertion rate | 100% | Positive Accuracy Rate | 75% |
Tube Name | R3 % Parent | CK1 | 0.02% | Display | 81.52% |
Ready to elevate your research with our yeast display library construction services?
to discuss your requirements and learn how our yeast display antibody library construction services can accelerate your research and development efforts.All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.