This product is an unconjugated anti-Human Ficolin-2 Monoclonal antibody (CTJS-9) generated from the Mouse. The antibody can be used for ELISA; WB.
Clonality | Monoclonal |
Clone | CTJS-9 |
Host Animal | Mouse |
Isotype | IgG1κ |
Immunogen | Recombinant human L-ficolin |
Species Reactivity | Human |
Applications | ELISA; WB |
Application Notes | WB: 1:100-1:2000 ELISA: 1:100-1:2000 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human Ficolin-2. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Liquid |
Size | 25; 100 µL |
Storage | 4°C |
Type | Primary Antibody |
Target Name | Ficolin-2 |
Alternative Names | Ficolin; Collagen/Fibrinogen Domain-Containing Protein 2; Serum Lectin P35; L-Ficolin; 37 KDa Elastin-Binding Protein; Ficolin-Beta; Ficolin-2; Ficolin B; Hucolin; EBP-37; FCNL; Ficolin (Collagen/Fibrinogen Domain Containing Lectin) 2 (Hucolin); Ficolin-B; P35 |
Gene ID | 2220 |
UniProt ID | Q15485 |
Introduction | Ficolin-2 is a protein that in humans is encoded by the FCN2 gene, which is initially identified as L-ficolin. L-Ficolin is an innate immunity pattern recognition molecule found in human serum. It binds to distinct pathogen-associated molecular patterns (PAMP) such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups, thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP (MBL-associated serine protease). |