Extracellular vesicles (EVs), including exosomes, are cell-derived nano or micrometer-sized monolayer or multilayer membrane structures. EVs contain bioactive cargoes such as nucleic acids, lipids, proteins, and carbohydrates, and play a key roleRead More…
Extracellular vesicles (EVs) are a highly heterogeneous class of membrane vesicles that participate in regulating various biological processes by transporting proteins, lipids, nucleic acids, and metabolites. According to differences in size andRead More…
Exosomes are secretory vesicles with a diameter of about 30 to 150 nanometers that play an important role in human health and disease. To better understand how cells release these vesicles, researchersRead More…
Neurodegenerative diseases (NDDs), such as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis, constitute a class of progressive diseases with complex pathogenesis. Traditional treatments face significant challenges due to drug delivery challenges.Read More…
Extracellular vesicles (EVs) secreted by all cell types are involved in the intercellular communication, delivering regulatory factors that influence cell and tissue phenotypes in both normal and diseased tissues. Therefore, EVs representRead More…
Vesiclepedia (http://www.microvesicles.org) stands as a comprehensive, web-based database, offering a compilation of DNA, RNA, proteins, lipids, and metabolites that have been identified or associated with extracellular vesicles (EVs) and extracellular particles (EPs).Read More…
A recent review was published in Nature Reviews Rheumatology delves into the promising therapeutic applications of mesenchymal stromal cell extracellular vesicles (EVs) in rheumatic diseases. Rheumatic diseases comprise a diverse range ofRead More…
Non-alcoholic fatty liver disease (NAFLD) is strongly linked to various cancers, including liver, breast, prostate, pancreatic, and colorectal cancer, surpassing its association with obesity alone. Patients with fatty liver disease exhibit aRead More…
Intercellular communication stands as a pivotal characteristic in tumor progression and metastasis. Extracellular vesicles (EVs), generated by diverse cells including tumor cells, serve as indispensable agents in cell-to-cell communication. They wield influenceRead More…
Exosomes Exosomes are single-layer membrane vesicles secreted by cells with a diameter of 30-200 nm, rich in proteins, lipids, nucleic acids, and carbohydrate complexes, and have obvious molecular heterogeneity. The production ofRead More…