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Bispecific Immunotoxin

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Bispecific immunotoxins (BITs) are a class of hybrid molecules consisting of the targeting bispecific antibody and the toxic moieties. The portion of bispecific antibody has two distinct targeting ligands and is responsible for the specificity of the immunotoxin. The targeting ligands bind molecular markers highly overexpressed in tumor cells but absent in normal cells. The toxic moieties used are usually derived from plant, bacteria, and fungi, most of them work by inhibiting protein synthesis. Plant toxins commonly used include ricin, gelonin, and pokeweed antiviral protein. And bacterial toxins include Pseudomonas exotoxin (PE) and diphtheria toxin (DT). The toxins in immunotoxins are delivered to the diseased tissue by the specific antibodies and kill the cells. In previous studies, immunotoxins have been proved to be a potential therapeutic tool for tumors. The dual-targeting moieties make bispecific immunotoxins (BITs) have more advantages than monospecific immunotoxins.

In addition to high-quality pre-made bispecific immunotoxin products, we also provide Bispecific Antibody-Toxin Fusion Protein Generation Service for customization requirement.

CAT# Product Name Species Reactivity BsAb Type Target 1 Target 2 INQUIRY
BSFV-MEL001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-BGN036 Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-BGN035 Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-BGN034 Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-BGN033 Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-BGN032 Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-BGN031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-BGN030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-BGN029 Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-BGN028 Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry
BSFV-BGN027 Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER2 Inquiry
BSFV-BGN026 Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR MET Inquiry
BSFV-BGN025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 PD1 Inquiry
BSFV-BGN024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 GLUT2 Inquiry
BSFV-BGN023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA GD2 Inquiry
BSFV-BGN022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-BGN021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-BGN020 Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD133 EGFR Inquiry
BSFV-BGN019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-BGN018 Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-BGN017 Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-BGN016 Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-BGN015 Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-BGN014 Recombinant Anti-HER2 x Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-BGN013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-BGN012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-BGN011 Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-BGN010 Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry
BSFV-BGN009 Recombinant Anti-EGFR x Anti-HER2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER2 Inquiry
BSFV-BGN008 Recombinant Anti-EGFR x Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR MET Inquiry
BSFV-BGN007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 PD1 Inquiry
BSFV-BGN006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 GLUT2 Inquiry
BSFV-BGN005 Recombinant Anti-CEA x Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA GD2 Inquiry
BSFV-BGN004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-BGN003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-BGN002 Recombinant Anti-CD133 x Anti-EGFR Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD133 EGFR Inquiry
BSFV-BGN001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-ABR036 Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-ABR035 Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-ABR034 Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-ABR033 Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-ABR032 Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-ABR031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-ABR030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-ABR029 Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-ABR028 Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry
BSFV-ABR027 Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER2 Inquiry
BSFV-ABR026 Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR MET Inquiry
BSFV-ABR025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 PD1 Inquiry
BSFV-ABR024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 GLUT2 Inquiry
BSFV-ABR023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA GD2 Inquiry
BSFV-ABR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-ABR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-ABR020 Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD133 EGFR Inquiry
BSFV-ABR019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-ABR018 Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-ABR017 Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-ABR016 Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-ABR015 Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-ABR014 Recombinant Anti-HER2 x Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-ABR013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-ABR012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-ABR011 Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-ABR010 Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry
BSFV-ABR009 Recombinant Anti-EGFR x Anti-HER2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER2 Inquiry
BSFV-ABR008 Recombinant Anti-EGFR x Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR MET Inquiry
BSFV-ABR007 Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 PD1 Inquiry
BSFV-ABR006 Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 GLUT2 Inquiry
BSFV-ABR005 Recombinant Anti-CEA x Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA GD2 Inquiry
BSFV-ABR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-ABR003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-ABR002 Recombinant Anti-CD133 x Anti-EGFR Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD133 EGFR Inquiry
BSFV-ABR001 Recombinant Anti-BCMA x Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-PAP036 Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-PAP035 Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-PAP034 Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-PAP033 Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-PAP032 Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-PAP031 Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-PAP030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-PAP029 Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-PAP028 Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry
BSFV-PAP027 Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER2 Inquiry
BSFV-PAP026 Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR MET Inquiry
BSFV-PAP025 Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 PD1 Inquiry
BSFV-PAP024 Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CTLA4 GLUT2 Inquiry
BSFV-PAP023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA GD2 Inquiry
BSFV-PAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 CD22 Inquiry
BSFV-PAP021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 CD22 Inquiry
BSFV-PAP020 Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD133 EGFR Inquiry
BSFV-PAP019 Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin BCMA TACI Inquiry
BSFV-PAP018 Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin VEGFR2 VEGFR3 Inquiry
BSFV-PAP017 Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin PDGFR2 VEGFR2 Inquiry
BSFV-PAP016 Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER3 IGF1R Inquiry
BSFV-PAP015 Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 HER3 Inquiry
BSFV-PAP014 Recombinant Anti-HER2 x Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER2 MET Inquiry
BSFV-PAP013 Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin HER1 HER3 Inquiry
BSFV-PAP012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 TFRC Inquiry
BSFV-PAP011 Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR IGF1R Inquiry
BSFV-PAP010 Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin EGFR HER3 Inquiry

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