| BSFV-MEL001 |
Recombinant Anti-BCMA x Anti-TACI Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-BGN036 |
Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-BGN035 |
Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-BGN034 |
Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-BGN033 |
Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-BGN032 |
Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-BGN031 |
Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-BGN030 |
Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-BGN029 |
Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-BGN028 |
Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
| BSFV-BGN027 |
Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER2 |
Inquiry |
| BSFV-BGN026 |
Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
MET |
Inquiry |
| BSFV-BGN025 |
Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
PD1 |
Inquiry |
| BSFV-BGN024 |
Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
GLUT2 |
Inquiry |
| BSFV-BGN023 |
Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CEA |
GD2 |
Inquiry |
| BSFV-BGN022 |
Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD20 |
CD22 |
Inquiry |
| BSFV-BGN021 |
Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD19 |
CD22 |
Inquiry |
| BSFV-BGN020 |
Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD133 |
EGFR |
Inquiry |
| BSFV-BGN019 |
Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-BGN018 |
Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-BGN017 |
Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-BGN016 |
Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-BGN015 |
Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-BGN014 |
Recombinant Anti-HER2 x Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-BGN013 |
Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-BGN012 |
Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-BGN011 |
Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-BGN010 |
Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
| BSFV-BGN009 |
Recombinant Anti-EGFR x Anti-HER2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER2 |
Inquiry |
| BSFV-BGN008 |
Recombinant Anti-EGFR x Anti-MET Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
MET |
Inquiry |
| BSFV-BGN007 |
Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
PD1 |
Inquiry |
| BSFV-BGN006 |
Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
GLUT2 |
Inquiry |
| BSFV-BGN005 |
Recombinant Anti-CEA x Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CEA |
GD2 |
Inquiry |
| BSFV-BGN004 |
Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD20 |
CD22 |
Inquiry |
| BSFV-BGN003 |
Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD19 |
CD22 |
Inquiry |
| BSFV-BGN002 |
Recombinant Anti-CD133 x Anti-EGFR Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD133 |
EGFR |
Inquiry |
| BSFV-BGN001 |
Recombinant Anti-BCMA x Anti-TACI Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-ABR036 |
Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-ABR035 |
Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-ABR034 |
Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-ABR033 |
Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-ABR032 |
Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-ABR031 |
Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-ABR030 |
Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-ABR029 |
Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-ABR028 |
Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
| BSFV-ABR027 |
Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER2 |
Inquiry |
| BSFV-ABR026 |
Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
MET |
Inquiry |
| BSFV-ABR025 |
Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
PD1 |
Inquiry |
| BSFV-ABR024 |
Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
GLUT2 |
Inquiry |
| BSFV-ABR023 |
Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CEA |
GD2 |
Inquiry |
| BSFV-ABR022 |
Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD20 |
CD22 |
Inquiry |
| BSFV-ABR021 |
Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD19 |
CD22 |
Inquiry |
| BSFV-ABR020 |
Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD133 |
EGFR |
Inquiry |
| BSFV-ABR019 |
Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-ABR018 |
Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-ABR017 |
Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-ABR016 |
Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-ABR015 |
Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-ABR014 |
Recombinant Anti-HER2 x Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-ABR013 |
Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-ABR012 |
Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-ABR011 |
Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-ABR010 |
Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
| BSFV-ABR009 |
Recombinant Anti-EGFR x Anti-HER2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER2 |
Inquiry |
| BSFV-ABR008 |
Recombinant Anti-EGFR x Anti-MET Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
MET |
Inquiry |
| BSFV-ABR007 |
Recombinant Anti-CTLA4 x Anti-PD1 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
PD1 |
Inquiry |
| BSFV-ABR006 |
Recombinant Anti-CTLA4 x Anti-GLUT2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
GLUT2 |
Inquiry |
| BSFV-ABR005 |
Recombinant Anti-CEA x Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CEA |
GD2 |
Inquiry |
| BSFV-ABR004 |
Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD20 |
CD22 |
Inquiry |
| BSFV-ABR003 |
Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD19 |
CD22 |
Inquiry |
| BSFV-ABR002 |
Recombinant Anti-CD133 x Anti-EGFR Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD133 |
EGFR |
Inquiry |
| BSFV-ABR001 |
Recombinant Anti-BCMA x Anti-TACI Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-PAP036 |
Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-PAP035 |
Recombinant Human Anti-PDGFR2 x Human Anti-VEGFR2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-PAP034 |
Recombinant Human Anti-HER3 x Human Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-PAP033 |
Recombinant Human Anti-HER2 x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-PAP032 |
Recombinant Human Anti-HER2 x Human Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-PAP031 |
Recombinant Human Anti-HER1 x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-PAP030 |
Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-PAP029 |
Recombinant Human Anti-EGFR x Human Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-PAP028 |
Recombinant Human Anti-EGFR x Human Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
| BSFV-PAP027 |
Recombinant Human Anti-EGFR x Human Anti-HER2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER2 |
Inquiry |
| BSFV-PAP026 |
Recombinant Human Anti-EGFR x Human Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
MET |
Inquiry |
| BSFV-PAP025 |
Recombinant Human Anti-CTLA4 x Human Anti-PD1 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
PD1 |
Inquiry |
| BSFV-PAP024 |
Recombinant Human Anti-CTLA4 x Human Anti-GLUT2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CTLA4 |
GLUT2 |
Inquiry |
| BSFV-PAP023 |
Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CEA |
GD2 |
Inquiry |
| BSFV-PAP022 |
Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD20 |
CD22 |
Inquiry |
| BSFV-PAP021 |
Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD19 |
CD22 |
Inquiry |
| BSFV-PAP020 |
Recombinant Human Anti-CD133 x Human Anti-EGFR Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
CD133 |
EGFR |
Inquiry |
| BSFV-PAP019 |
Recombinant Human Anti-BCMA x Human Anti-TACI Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
BCMA |
TACI |
Inquiry |
| BSFV-PAP018 |
Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
VEGFR2 |
VEGFR3 |
Inquiry |
| BSFV-PAP017 |
Recombinant Anti-PDGFR2 x Anti-VEGFR2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
PDGFR2 |
VEGFR2 |
Inquiry |
| BSFV-PAP016 |
Recombinant Anti-HER3 x Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER3 |
IGF1R |
Inquiry |
| BSFV-PAP015 |
Recombinant Anti-HER2 x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
HER3 |
Inquiry |
| BSFV-PAP014 |
Recombinant Anti-HER2 x Anti-MET Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER2 |
MET |
Inquiry |
| BSFV-PAP013 |
Recombinant Anti-HER1 x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
HER1 |
HER3 |
Inquiry |
| BSFV-PAP012 |
Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
gp40 |
TFRC |
Inquiry |
| BSFV-PAP011 |
Recombinant Anti-EGFR x Anti-IGF1R Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
IGF1R |
Inquiry |
| BSFV-PAP010 |
Recombinant Anti-EGFR x Anti-HER3 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) |
Human |
Bispecific Immunotoxin |
EGFR |
HER3 |
Inquiry |
Bispecific immunotoxins (BITs) are a class of hybrid molecules consisting of the targeting bispecific antibody and the toxic moieties. The portion of bispecific antibody has two distinct targeting ligands and is responsible for the specificity of the immunotoxin. The targeting ligands bind molecular markers highly overexpressed in tumor cells but absent in normal cells. The toxic moieties used are usually derived from plant, bacteria, and fungi, most of them work by inhibiting protein synthesis. Plant toxins commonly used include ricin, gelonin, and pokeweed antiviral protein. And bacterial toxins include Pseudomonas exotoxin (PE) and diphtheria toxin (DT). The toxins in immunotoxins are delivered to the diseased tissue by the specific antibodies and kill the cells. In previous studies, immunotoxins have been proved to be a potential therapeutic tool for tumors. The dual-targeting moieties make bispecific immunotoxins (BITs) have more advantages than monospecific immunotoxins.
