Tandem scFvs are a class of bispecific antibody fragments. Two or more moieties of scFv string together to form tandem scFv, which has 1+1 (+1…) antigen-binding. scFvs are fused by a helical linker or a flexible linker. The format of tandem scFvs can be defined by the orientation of the VH and VL domain in the two individual scFvs (i.e., VL-VH or VH-VL) and the connecting linker. Without Fc domain, the smaller size of tandem scFv gives it a short half-life. Meanwhile, it also ensures a closer proximity to two or more targets.
The format of tandem scFvs has been extensively used in cancer immunotherapy.
In addition to high-quality pre-made tandem scFv products, we also provide Tandem scFv Generation Service for customization requirement.
Browse Tandem scFv based on alphabetical listing:
A
B
C
D
E
F
G
H
I
K
M
N
O
P
T
V
Welcome! For price inquiries, we will get back to you as soon as possible.
INQUIRYSERVICES
PRODUCTS
PLATFORMS