Description
This cell line expresses a surface human CD40 and an NF-kappaB luciferase reporter construct that are stably integrated into the genome of HT1080.The firefly luciferase gene is controlled by 4 copies of NF-kappaB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-kappaB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.
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