Product Type: Immune Animal Model
Short Decsription: This model can achieve the depletion of mouse T\B\NK cells by silencing NOD, SCID, and IL2Rg.
Product Type: Immune Animal Model
Short Decsription: This model achieves the goal of MHC-I knockout and GvHD reduction in hu-PBL mice (mice treated with PBMCs) by silencing H2-Db/H2-Kd.
Product Type: Immune Animal Model
Short Decsription: This mouse model enables MHC-I/II knockout and GvHD delay in hu-PBL mice (mice treated with PBMCs) by silencing H2-DB/H2-Kd/H2-Ab1.
Product Type: Immune Animal Model
Short Decsription: This mouse model enables irradiation-free hematopoietic stem cell engraftment and improved human erythropoiesis and platelet formation through Kit W41 mutation.
Product Type: Immune Animal Model
Short Decsription: This model implements the function of impair the murine DC development by silencing FIk2/FLT3.
Product Type: Immune Animal Model
Short Decsription: In this model, Tslp is expressed through K14 pramoter, thereby achieving lymph node development in mice.
Product Type: Immune Animal Model
Short Decsription: This model is based on the expression of mIL2rg in Lti cells to achieve lymph node development in mice.
Product Type: Immune Animal Model
Short Decsription: This model achieves knockout mouse Fc-mediated function by silencing FcgRs (FcgR I/II/III/IV).
Product Type: Immune Animal Model
Short Decsription: This model implements human CD8 T cell education by knocking in HLA A2.
Product Type: Immune Animal Model
Short Decsription: This model implements human CD4 T cell education by knocking in HLA DR1.
Product Type: Immune Animal Model
Short Decsription: This model implements human NK education and HLA-E-restricted CD8+ T cell responses by knocking in HLA E.
Product Type: Immune Animal Model
Short Decsription: This mouse model enables irradiation-free hematopoietic stem cell engraftment and improved human erythropoiesis and platelet formation through over-expression of hTHPO.
Product Type: Immune Animal Model
Short Decsription: This model enables human DC development in NSG (FIk2/FLT3 null) mice by humanizing FLT3L.
Product Type: Immune Animal Model
Short Decsription: This model helps to study adoptive cellular immunity in solid tumors by overexpressing hIL2.
Product Type: Immune Animal Model
Short Decsription: This model improves human myeloid cell development in hu-HSC (CD34⁺ HSCs treatment mice) mice by overexpressing hIL3/hCSF2.
Product Type: Immune Animal Model
Short Decsription: This model improves thymopoiesis in thymus and human B cell development by humanizing the IL7 gene.
Product Type: Immune Animal Model
Short Decsription: This model improves numbers of memory CD8T cells and human NK development/proliferation by humanizing the IL15 gene.
Product Type: Immune Animal Model
Short Decsription: This model aims to reduce anemia in in myeloid-enhanced mice and study the cytotoxicity of anti-CD47 antibodies by humanizing the CD47 gene.
Product Type: Immune Animal Model
Short Decsription: This model is used to study the albumin-fusion protein ar albumin-binding protein by humanizing the FcRN and Albumin genes.
Product Type: Immune Animal Model
Short Decsription: This model achieves the effect of damaging the liver of mice to promote the engraftment of human hepatocytes by expressing HSVtk in liver cells.
