Metabolic changes, also named metabolism reprogramming, are the most obvious alterations in many types of cancer. Tumor metabolism reprogramming involves multiple signaling pathways that contribute to the unique metabolic signature observed in cancer cells. Understanding the mechanisms behind tumor metabolism reprogramming can help identify new targets for cancer treatment. At Creative Biolabs, we utilize a variety of techniques, including metabolite profiling, metabolomics, and flux analysis, to gain insights into tumor metabolism. We also provide services such as PET to visualize and measure tumor metabolism in vivo.
Fig.1 Tumor metabolism reprogramming.1
We can assist you with the following:
Creative Biolabs offers comprehensive Tumor Metabolism Characterization services, which include the following:
Through an in-depth analysis of the metabolic pathways of tumor cells, potential therapeutic targets are identified, providing a scientific basis for tumor therapy.
This combines multiple sources of scientific data such as genomes, transcription profiles, and protein expression data to comprehensively reveal the unique signature of tumor metabolism and inform strategies for personalized therapy.
This involves detecting metabolites in tumor cells and assessing the activity of metabolic enzymes, enabling an understanding of tumor cell metabolic status and supporting the development of novel anti-tumor drugs.
This in-depth exploration of the metabolic characteristics of distinct sub-cellular structures within tumor cells provides valuable insights into the genesis, development, and metastasis of tumors.
This involves a comprehensive examination of the interaction between tumor cells and their surrounding micro-environments, revealing how tumor cells obtain nutrients and energy, and suggesting potential avenues for designing innovative treatment strategies.
The insights gained from functional genetic screens have led to the identification of novel targets for cancer therapy. At Creative Biolabs, we provide multi-dimensional and comprehensive technologies to explore the functional characterization of metabolic genes and enzymes for cancer and metabolic diseases. Our technologies, based on CRISPR/Cas9, RNAi, and small molecule inhibitors, have been successfully used to identify cancer metabolic phenotypes and metabolic dependencies. We offer a range of services, including functional screening, small molecule inhibitor screening, and characterization of metabolic enzymes.
Creative Biolabs offers comprehensive tumor model construction services for cancer metabolism research. Our services support the development of more effective treatment methods by enabling researchers to better understand the metabolic process of cancer cells. We specialize in the construction of 2D in vitro cancer metabolic models, 3D in vitro cancer metabolic models, ex vivo organotypic tumor slice cultures, and animal models. These services are designed to provide an accurate representation of human cancer conditions, enabling researchers to study tumor metabolism in vitro and in vivo. By utilizing our tumor model construction services, researchers can gain a deeper understanding of cancer cell metabolism and identify new targets for cancer treatment.
At Creative Biolabs, we provide various noninvasive imaging modalities to visualize and measure tumor metabolism in vivo in animal models. Our methods include PET-CT, micro-CT, MRI, optical imaging, and so on.
Please feel free to contact us. We are pleased to provide support and services for your project.
Reference
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