Human BAFF-R Recombinant Cell Line (Medium Expression), CHO-K1 (CAT#: IOC-LX089)

Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant human BAFF-R-CHO K1 cell line stably expressing full length human BAFF-R/TNFRSF13C receptor (GenBank Accession: NM_052945.3). Which can be used in binding assays and functional assay.

Stable cell lines for increased reliability and reproducibility;
Protein expression at the cell surface validated by FACS or WB;

• Screen for activators or inhibitors of antibody-mediated signaling for immunotherapy research and drug discovery.
• Characterize BAFF-R antibodies and ligands for binding assays.

Human

CHO-K1

BAFF-R

BAFF Receptor (B-cell activating factor receptor, BAFF-R) is an essential factor for B cell maturation and survival. In humans it is encoded by the TNFRSF13C gene. BAFF-R function is impressively documented in humans by a homozygous deletion, which leads to an almost complete block of B cell development at the stage of immature/transitional B cells. The resulting immunodeficiency is characterized by B-lymphopenia, agammaglobulinemia, and impaired humoral immune responses.