Description
Creative Biolabs provides a reliable ethically sourced, ready-to-use, human primary Central Memory CD8+ T cells (CD3+CD8+CD45RO+CD62L+). These cells are isolated from peripheral blood mononuclear cells (PBMCs) of normal donors. This product allows for study in numerous immunity research areas.
Background
Memory CD8+ T cells were originally thought to exist as two populations (effector and central memory). Central memory CD8+ T cells, which express the secondary lymphoid organ-homing molecules CCR7 and CD62L, are mainly found within the spleen and lymph nodes, lack immediate effector function and have increased ability to generate secondary immune responses. It control systemic secondary infections and can protect from chronic infection and cancer as a result of their stem-cell-like capacity to expand, differentiate, and self-renew.
Species
Human
Cell type
Central memory CD8+ T cells
Source
Peripheral Blood

For Research Use Only | Not For Clinical Use

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