Description
Creative Biolabs offers several bioanalysis and inhibitor screening assay kits for customers, which will help researchers to accelarate the studies in immunology and onconology areas. The recombinant expression vectors are designed to express human engineered T cell receptor (TCR) activator and woodchuck (groundhog, Marmota monax) PD-L1 (GenBank Accession #HQ403651) in mammalian cells. The transfected cells can be used in conjunction with Woodchuck PD-1/NFAT Reporter/Jurkat T cells to study the interactions of PD-1 with PD-L1 ligand in a cellular context and screen for modulators of this signaling pathway.
Features
Available to study immunology signaling pathway, monitor and screen small molecular.
Applications
• Screen for activators or inhibitors of PD-1 signaling in a cellular context
• Characterize the biological activity of PD-1 and its interactions with ligands
Target
PD-L1 (Woodchuck) / TCR
Research Areas
Cell Signaling Pathway, Immunology, Onconology

For Research Use Only | Not For Clinical Use

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