Bioconjugation with engineered unnatural amino acids In addition to the sulfur monoclonal antibody technique, the addition of non-standard amino acids (ncAA) provides another possibility for site-specific conjugation. This technique uses amino acidsRead More…
Site-specific bioconjugation of engineered antibodies Advances in bioorthogonal chemistry and protein engineering have contributed to the production of more uniform ADC. Although there are many attachment methods available for natural McAbs, site-specificRead More…
Chemical modification of specific in situ antibody The natural structure of monoclonal antibodies provides a variety of possibilities for bioconjugation. The chemical-based, specific natural (non-engineered) antibody conjugation has some benefits in thatRead More…