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Category Archives: Chimeric Antigen Receptor Research

20Dec/18

Blocking GM-CSF Protein Is Expected to Improve CAR-T Cell Therapy

December 20, 2018Chimeric Antigen Receptor Research, NewsCAR-T, GM-CSFbiocart

In a new study, researchers from the Mayo Clinic in the United States have developed a new strategy that may improve the performance of chimeric antigen receptor T (CAR-T) cell therapy inRead More…

22Nov/18

CAR-T cells Armored with Mini PD-1 Antibody Exhibit Stronger Anti-Tumor Efficacy

November 22, 2018Chimeric Antigen Receptor Research, NewsArmored CAR, CAR-T, PD-1biocart

Recently, scientists from the Memorial Sloan Kettering (MSK) Cancer Center announced that they have established the latest engineered cells with powerful efficiency, which combine chimeric antigen receptor (CAR) -T cells and checkpointRead More…

25Oct/18

Fights Cancer More Effectively——Supercharged Natural Killer Cell (CAR-iNKT)

October 25, 2018Chimeric Antigen Receptor Research, NewsCAR-T, CAR19-iNKT, CD19, CD1dbiocart

Recently, a study conducted by the research team from the Imperial College London published in the Cancer Cell showed that supercharged natural killer (NK) cells capable of mass production can effectively fightRead More…

30Aug/18

Two CAR-T Products Were Approved by the European Union for the First Time

August 30, 2018Chimeric Antigen Receptor Research, NewsCAR products, CAR-T, chimeric antigen receptor T cell therapybiocart

Cancer immunotherapy that is given to attention long time has recently made tremendous progress. Novartis’s Kymriah and Gilead’s Yescarta, two star CAR-T products, were approved by the European Union (EU) and becameRead More…

29Aug/18
Uses of Cancer Biomarkers

Review: The Expansion of Targetable Biomarkers for CAR T Cell Therapy

August 29, 2018Chimeric Antigen Receptor ResearchCAR T biomarker, CAR-T, CAR-T therapy, CD19, CD19 CAR, Chimeric antigen receptorbiocart

A recently published report summarizes the biomarker targets in both hematological and solid malignancies for CAR T cell therapy and discusses potential new biomarker target. A biomarker is an integral part ofRead More…

06Aug/18

Cytokine Release Syndrome Caused by CAR-T Therapy

August 6, 2018Chimeric Antigen Receptor ResearchCAR-T, CAR-T treatment, Chimeric antigen receptorbiocart

Chimeric antigen receptor T cell (CAR-T) therapy is a novel cellular immunotherapy method that introduces chimeric antigen receptors and costimulatory molecules targeting specific targets into T cells by gene editing technology. TumorRead More…

24Jul/18

CAR-NK: Safer, Cheaper and Better Anti-cancer Drug

July 24, 2018Chimeric Antigen Receptor ResearchCAR-NK cell, CAR-T cell therapy, in vivo animal testingbiocart

At the end of June this year, the CAR-NK cell, a new immune cell, was reported as the third CAR cell to fight against cancer after CAR-T cells and CAR-macrophage cells. TheRead More…

31May/18

Hot Issues Tracking—Present and Future of Oncolytic Virus

May 31, 2018Chimeric Antigen Receptor ResearchCAR-T, Oncolytic virus therapy, Oncolytic viruses (OVs)biocart

On May 2, Johnson & Johnson, a pharmaceutical giant, announced that it has invested $1 billion in the acquisition of BeneVir Biopharm, a biotech-company dedicated to oncolytic virus immunotherapy research. This newsRead More…

30May/18

What Is Immunotherapy?

May 30, 2018Chimeric Antigen Receptor ResearchCAR-T, chimeric antigen receptor T-cell, high affinity TCRs, Oncolytic virus immunotherapybiocart

A 72-year-old Connecticut citizen Bob Carlson was diagnosed with lung cancer four years ago. The doctor estimates that he will not live longer than two years. He tried a variety of programsRead More…

28May/18

CAR-T: A Constantly Optimized Anti-cancer Therapy

May 28, 2018Chimeric Antigen Receptor ResearchBCMA, CAR-T, CD19, chimeric antigen receptor T-cell immunotherapy, NY-ESO, select different scFvsbiocart

CAR-T cell immunotherapy, the chimeric antigen receptor T-cell immunotherapy, is a highly efficient and advanced cell immunotherapy. The principle is to genetically modify the immune cell T cells in patients to killRead More…

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  • Advancements and Challenges in CAR-Macrophage Therapy: A New Frontier in Cancer Immunotherapy
  • NK Cell Surveillance Limits T Cell Responses: Implications for Cancer Immunotherapy
  • High-throughput Discovery of Tumor-Reactive T Cell Receptors: Advancing Personalized Cellular Immunotherapy
  • Overcoming Resistance: Enhancing CAR-T Therapy for AML with TP53 Mutations

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