Tag Archives: chimeric antigen receptors (CARs)

10Jan/18

What Is CD19 Antigen?

January 10, 2018Chimeric Antigen Receptor Researchacute lymphoblastic leukemia (ALL), CAR-T, CD19 antigen, chimeric antigen receptors (CARs)biocart

As the data from clinicaltrials.gov shows, CD19 antigen is the most frequently used biomarker in CAR-T cell therapy clinical trials for hematological malignancy such as leukemia and lymphoma. According to our statistics report, overRead More…

09Jan/18

Figure 1. Chimeric antigen receptor design and evolution

What the Next Generation T Cell Therapy Looks Like

January 9, 2018Chimeric Antigen Receptor ResearchCAR T cell design, CAR T technology, chimeric antigen receptors (CARs)biocart

T cell receptors (TCRs) provide a recognition signal for T cells complemented by a co-stimulatory signal that can provide an on/off signal to regulate the activation of T cells. Since Medawar andRead More…

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