Cascade activation of the complement system is one of the key mechanisms of the immune system against pathogenic infections. It is a complex network of plasma proteins, including inflammatory peptides, proteases, andRead More…
Complement, named because it assists antibodies in removing pathogens, is a group of about 20 proteins found in plasma. Complement is mainly derived from the liver or certain cell membrane proteins andRead More…
Bordet, the winner of the 1919 Nobel Prize in Physiology or Medicine, found that when serum was heated to 56°C, it lost its ability to kill bacteria, even though the antibodies inRead More…
Myasthenia gravis (MG) is an autoimmune disease characterized by an acquired neuromuscular junction transmission disorder mediated by autoantibodies. MG patients are mainly characterized by fluctuating weakness and fatigue of skeletal muscles, withRead More…
There are three complement activation pathways in the complement system, that is, the classical pathway, the alternative pathway, and the lectin pathway. The three pathways have different origins, but they cross eachRead More…
According to statistics, the prevalence of atypical hemolytic uremic syndrome (aHUS) is about seven in one million. The majority of aHUS have complement-related factor gene mutations, and the etiology of about 6%Read More…