Tag Archives: PROTAC molecules

02Mar/23

Research Progress of PROTAC in the Development of Antineoplastic Drugs

March 2, 2023PROTAC ResearchKinases, Nuclear Receptors, PROTAC molecules, Target Protein Ligandbiolabs

Compared with traditional drugs, PROTAC molecules have many advantages. PROTAC molecule is covalently linked by the target protein ligand and E3 ubiquitin ligase ligand. After binding to the target protein, E3 ligaseRead More…

14Sep/22

PROTACs Provide Both Academia and Business a Tremendous Opportunity

September 14, 2022protac reviewsPROTAC moleculesbiolabs

In the past 20 years, PROTAC has ushered in a period of rapid development, especially since the successful degradation of BET protein by dBET1 PROTAC with pomalidomide as the ligand of anRead More…

27Jun/22

Newly Discovered: The First Microbial-Derived PROTAC Molecule

June 27, 2022PROTAC News, PROTAC ResearchMicrobial-Derived PROTAC, PROTAC moleculesbiolabs

PROTAC (Proteolysis-Targeting Chimera) technology, by linking E3 ubiquitin ligase to the target protein, leads to the ubiquitin modification of the target protein, which is broken down into peptides and amino acids byRead More…